Blog Articles

Sarcopenic Obesity: Why Losing Weight Without Preserving Muscle Ages You Faster

Losing weight without preserving muscle can accelerate aging. How sarcopenic obesity develops, why the scale misses it, and what testing catches it.

August 23rd, 2026

TPE vs. Regular Blood Donation: Does Giving Blood Do Anything for Longevity?

Does donating blood do what therapeutic plasma exchange does? A claim-by-claim look at where the comparison holds up and where it breaks down.

August 18th, 2026

Rapamycin, Metformin, and TPE: Can You Combine Longevity Protocols Safely?

Can rapamycin, metformin and TPE be combined safely? What each targets, how they interact, and the monitoring a combined longevity stack requires.

August 18th, 2026

Why Your Annual Physical Bloodwork Missed Everything: Standard Labs vs. Precision Diagnostics

A standard annual physical screens for disease, not trajectory. What precision diagnostics adds across glucose, lipids, inflammation and hormones.

August 18th, 2026

Peptide Therapy for Longevity: Separating Evidence from Hype

Peptide therapy for longevity: where the evidence is genuinely strong, where it gets thin, and what to ask before starting. Liondale Medical, NYC.

August 7th, 2026

Longevity Labs 101: Which Biomarkers Actually Predict Healthspan

Which biomarkers actually predict healthspan: hs-CRP, fasting insulin, HOMA-IR, HbA1c, and how often to retest. Liondale Medical, NYC.

August 7th, 2026

Continuous Glucose Monitoring for Non-Diabetics: What It Actually Reveals About Aging

What a continuous glucose monitor reveals for non-diabetics: glucose variability, post-meal spikes, and how the data guides care. Liondale Medical, NYC.

August 3rd, 2026

Building a Personalized Longevity Plan: What Precision Diagnostics Actually Measure

What precision diagnostics actually measure when building a personalized longevity plan in NYC, and how results guide care. Liondale Medical.

July 31st, 2026

NAD+ IV Therapy: How It's Different From a Standard Vitamin Drip

How NAD+ IV therapy differs from a standard vitamin drip: mechanism, infusion time, what it targets, and candidacy. Liondale Medical, NYC.

July 31st, 2026

Regenerative Medicine 101: What It Actually Means for a Longevity Patient

What regenerative medicine actually means for a longevity patient: ozone therapy, NAD, TPE, and how they fit a plan. Liondale Medical, NYC.

July 29th, 2026

Menopause and Longevity Medicine: A Concierge Approach to Symptom Management

Concierge menopause care in NYC: comprehensive testing, hormone therapy options, and individualized symptom management. Liondale Medical.

July 29th, 2026

Bioidentical Hormones vs. Synthetic Hormones: Understanding the Difference

Bioidentical vs. synthetic hormones: what the terms actually mean, why the distinction matters clinically, and how to choose. Liondale Medical, NYC.

July 24th, 2026

Testosterone Replacement Therapy for Men: What the Process Actually Involves

Testosterone replacement therapy for men in NYC: evaluation, lab testing, treatment options, and ongoing monitoring. Liondale Medical.

July 24th, 2026

Concierge Medicine Explained: What Makes It Different From Traditional Primary Care

Concierge medicine explained: how it differs from traditional primary care — panel size, access, diagnostics, insurance, and cost. Liondale Medical.

July 23rd, 2026

Finding Therapeutic Plasma Exchange Near You in NYC

Finding therapeutic plasma exchange (TPE) near you in NYC: how to evaluate providers, what to expect, safety, and why location matters. Liondale Medical.

July 21st, 2026

What Is EBO2 Therapy? How It Works and What to Expect

EBO2 therapy in NYC: how extracorporeal blood oxygenation and ozonation works, what to expect in a session, plus safety and candidacy. Liondale Medical.

July 21st, 2026

How We Measure TPE Results: The Labs Behind Every Session

Most TPE clinics perform the procedure and send you home. At Liondale, every session is bracketed by a pre-treatment baseline draw and a post-treatment follow-up panel. We measure the same markers before and after: CRP, IL-6, fibrinogen, a metabolic panel, a lipid panel, and where clinically relevant, epigenetic clock biomarkers...

May 28th, 2026

Is Therapeutic Plasma Exchange Safe? Who Should, and Shouldn't, Consider It

Yes, therapeutic plasma exchange has a strong medical safety record when it is performed in the right setting, with the right screening, and for the right patient. Large retrospective studies report serious adverse events in roughly 0.12% of procedures, and TPE has decades of clinical use behind it in both autoimmune...

May 27th, 2026

Why Patients Choose Liondale Medical for TPE in NYC

Liondale Medical is one of only three NYC practices currently offering therapeutic plasma exchange for longevity. What separates it is not a louder claim. It is the care model: physician-led oversight by Lionel Bissoon, D.O., a Circulate Health partnership that informs how the practice approaches TPE, pre- and...

May 27th, 2026

Concierge Longevity Medicine in NYC

Concierge longevity medicine is physician-led, lab-driven care for patients who want a real medical strategy for aging well, not a menu of trendy treatments sold one by one. At Liondale Medical on the Upper West Side, Dr. Lionel Bissoon, D.O., builds that strategy around baseline testing, direct physician oversight...

May 27th, 2026

How to Remove Microplastics From Blood: Can TPE Help?

There is no proven everyday intervention for removing microplastics from blood. The honest answer is that researchers are still working out what microplastic accumulation in human tissue means clinically, let alone how to address it. Therapeutic plasma exchange is being discussed in this context because it physically removes and replaces the plasma fraction of blood...

May 18th, 2026

What the 2025 TPE Clinical Trial Actually Proved, and What It Didn't

Does TPE work? Based on the best direct human evidence we have right now, yes, therapeutic plasma exchange appears to improve biological age biomarkers under controlled study conditions. In the May 2025 Aging Cell trial, TPE plus IVIG reduced biological age by an average of 2.61 years, while TPE alone reduced it by 1.32 years...

May 18th, 2026

TPE vs. NAD+ vs. Stem Cells: How to Choose the Right Anti-Aging Treatment

If you are comparing longevity treatments, therapeutic plasma exchange has the strongest published case for measurable biological age reduction among the options on this list. NAD+ IV therapy is broader, less aggressive, and far less expensive, which makes it a sensible entry point for many patients...

May 18th, 2026

The Hidden Signs Your Hormones Are Aging Faster Than You Are

Aging isn’t just about a number. Sometimes your hormones run ahead of the timeline, quietly shifting your energy, mood, metabolism, and more. Here are some hidden signs that your hormones are aging quickly.

Apr 10th, 2026

Anxious About Aging? 5 Proactive Steps You Can Take for a Healthier Future

If the idea of getting older makes you anxious, you’re not alone. The good news? While you can’t stop time, you can take steps now to make your future self healthier, stronger, and more at ease. Here are five proactive moves for a healthier future.

Feb 13th, 2026

Rekindle Your Spark: How BHRT Can Improve More Than Just Your Mood

Feeling “off” lately but can’t put your finger on why? Low energy, brain fog, poor sleep, or mood swings are often brushed off as stress or aging. But hormones may be part of the story. If so, BHRT (bioidentical hormone replacement therapy) can help.

Jan 9th, 2026

Stop Feeling Tired: Could NAD+ IV Therapy Be Your Energy Solution?

You stayed up late scrolling. Now, you’re tired, lack focus, and feel overwhelmed by simple tasks. Enter NAD+ IV therapy, a revitalizing treatment that recharges cells and boosts your energy. Here’s why you should consider NAD+.

Dec 10th, 2025

Why Your Gut Health Affects Everything (Even Your Mood)

Your gut isn’t just about digesting last night’s dinner. It’s home to trillions of bacteria (your microbiome) that support entire body systems — and even help elevate your mood. If your gut's out of whack, you may feel a bit off. Here’s why.

Nov 6th, 2025

How to Shift From Sick Care to True Health Care

Many of us don’t call our doctor until something feels “off.” That’s sick care — reactive, short-term fixes after symptoms show up. Instead, true health care focuses on smarter choices aimed at prevention.

Oct 15th, 2025

Preventing Alzheimer’s Starts Earlier Than You Think

Alzheimer’s disease is the most common form of dementia — AKA, memory loss that interferes with your quality of life. It affects millions, mostly older adults, and right now there’s no cure. But there’s good news: there are ways to reduce your risk. 

Sep 22nd, 2025

What to Expect from Testosterone Shots

Curious about testosterone therapy but not sure if receiving shots is right for you? Testosterone replacement therapy can dramatically alter your life if you struggle with low T. Here’s why.

Aug 4th, 2025

The Link Between Hormones and Headaches During Workouts

So you finally made it to the gym. You’re mid-squat or halfway through spin class, and bam — a headache. Not exactly the endorphin rush you signed up for. What gives? Your hormones and workouts are in a complicated relationship. Here’s why.

Jul 9th, 2025

The Top Places Your Hair Falls Out When the Cause Is Hormonal

If your hair sheds at a scary pace, your hormones might be the culprit. Find out the top places where hormonal hair loss occurs — plus why it’s happening, and how to stop it.

Jun 2nd, 2025

5 Ways IV Therapy Can Keep You Healthy

Let’s talk about the extra fluids and nutrients your body didn’t know it needed. Intravenous (IV) therapy infuses fluids, vitamins, or medications straight into your bloodstream. Here are some reasons to choose IV therapy for better health.

May 2nd, 2025

3 Reasons to Consider Ozone Therapy

Ozone therapy (yes, the stuff that makes up part of our atmosphere) has been making waves for its potential health benefits. The idea? It increases oxygen in the body, offering an array of health benefits. Here’s why you should consider it.

Apr 2nd, 2025

Warning Signs of a Testosterone Imbalance

Testosterone plays a key role in energy, mood, muscle mass, and sexual function. But especially as we age, testosterone levels can change. Discover the 12 warning signs of testosterone imbalance that may warrant a doctor visit.

Mar 2nd, 2025

8 Reasons Why Bioidentical Hormone Replacement Therapy May Be Right for You

You don’t have to accept weight gain, muscle loss, and thinning hair as inevitable signs of aging. Bioidentical hormone replacement therapy may offer the solution you’re looking for, helping you age gracefully while maintaining a youthful appearance.

Feb 14th, 2025

5 Anti-Aging Benefits of NAD Therapy

By the time you’re middle-aged, you have about half of the powerful co-enzyme NAD you had in your youth. NAD therapy restores your NAD levels, giving you impressive anti-aging benefits.

Jan 6th, 2025

Keep Taking the Testosterone - Financial Times

High T: Lionel Bissoon (above) has seen a rise in demand for testosterone from Wall Street workers.

Apr 22nd, 2020

Lyme Disease: Conflicted Experts, Patients in the Crossfire

One day, Meghan O’Rourke started experiencing “electrical shocks” throughout her legs and arms - a spasming and itchiness that left doctors confused. Like many other patients, the doctors all sent her home with simple hypotheses and a “wait-and-see” treatm

Apr 22nd, 2020

Regenerative Cellular Medicine to Treat Frailty in Old Age

Regenerative Cellular Medicine could Treat Frailty in Old Age

Apr 22nd, 2020

How Wall Street and tech bros are staying forever young: Dr. Lionel Bissoon's interview with New Yor

Want to know how to stay young, fit and energized? Learn how all the major New York executives do it in Dr. Lionel Bissoon's interview with the New York Post, "How Wall Street and tech bros are staying forever young." Read the original article on the New

Apr 22nd, 2020

Hormone Replacement Therapy for Women in their 40s Could Prevent Alzheimer’s

Women make up the majority of Alzheimer’s cases. While scientists don’t fully understand all of the mechanisms behind women’s increased risk factor, researchers have found one treatment to help curb the onset of Alzheimer’s: hormone replacement therapy.

Apr 22nd, 2020

Simple Anti-Aging tips from Dr. Bissoon

Could your sleep habits cause wrinkles? What other lifestyle choices will keep us looking forever young? Dr. Lionel Bissoon was invited to weigh in on LIVESTRONG.COM's list of top Anti-Aging tips. Which of these skin sins are you committing?

Apr 22nd, 2020

Watch! Magazine interviews Dr. Bissoon on his Top 5 Anti-Aging Tips for Men

Watch! Magazine got in touch with Dr. Bissoon to find out his top 5 anti-aging tips for men. Read the article below, or download the article in its full form.

Apr 22nd, 2020

Watch Magazine features Dr. Lionel Bissoon

In the Body & Soul section of Watch Magazine (December 2012), an Anti-Aging article highlights Dr. Lionel Bissoon's Anti-Aging Therapies. Read his advice below, or download a PDF of the article!

Apr 22nd, 2020

BBC Brasil: Executives in the U.S. try to slow aging hormones

Executives and professionals in the United States have been seeking a controversial and expensive hormone replacement therapy to combat effects usually associated with stress and aging.

Apr 22nd, 2020

Diet Plan With HCG, a Fertility Hormone, Has Fans and Critics - New York Times

Every morning, Kay Brown engages in a ritual similar to a heroin addict’s, or a diabetic’s: she sticks herself with a syringe. Only hers contains hCG, a pregnancy hormone.

Apr 22nd, 2020