EBO2 And 10 PASS OZONE
Liondale Medical
A Private Medical Practice located in Upper West Side, New York, NY
Medical ozone therapy has the remarkable ability to heal numerous health conditions, including the symptoms of many diseases that defy conventional treatments.
At Liondale Medical on the Upper West Side of Manhattan in New York City, Lionel Bissoon, DO, offers medical ozone therapy using several methods, including the innovative and potent 10-pass ozone procedure and the EBO2 procedure.
10 PASS OZONE AND EBO2
Ozone is a powerful oxygen therapy capable of relieving pain, fighting bacterial infections, and treating a variety of health conditions. Once ozone is inside your body, it triggers cellular reactions that activate healing. Medical ozone therapy also raises oxygen levels in your blood, stimulates your immune system, fights inflammation, and boosts energy.
At Liondale Medical you get access to two of the most advanced forms of ozone based treatment available today, 10 pass ozone therapy and EBO2. Here is what each one involves, who they are designed for, and what to expect if you are considering either treatment.
What is ozone therapy
Ozone therapy uses medical grade ozone, a naturally occurring molecule made of three oxygen atoms, to trigger a cascade of beneficial reactions in the body. When properly administered, it can raise blood oxygen levels, activate antioxidant defenses, reduce inflammation, and support the immune system's ability to fight off chronic infections. It has become a popular option among people looking for a non drug approach to chronic fatigue, autoimmune symptoms, and general anti-aging support, particularly when other treatments have not delivered the results they were hoping for.
10 pass ozone therapy
Ozone therapy can be administered using several possible methods, but 10 pass is one of the most effective. When you receive 10 pass ozone therapy, a precise amount of your blood is drawn into a small hyperbaric machine that mixes the blood with ozone under high pressure. The pressure allows your red blood cells to absorb more oxygen than they would through standard ozone delivery methods.
The ozonated blood is returned to your body, and the process is repeated, pulling more blood, ozonating it under pressure, and returning it again. This cycle repeats 10 times, which is why it is called 10 pass ozone therapy. With this method, you receive a more potent, more concentrated dose of ozone compared to other delivery methods, since each pass adds another layer of oxygenation to your blood before it is returned to circulation.
Liondale Medical was one of the first facilities in New York City to offer hyperbaric ozone 10 pass therapy. Many patients do this treatment monthly for its anti-aging benefits, while patients dealing with chronic fatigue and Lyme disease are often treated one or two times a week until they are symptom free.
EBO2, a complete oil change for your blood
EBO2 stands for Extracorporeal Blood Oxygenation and Ozonation. This advanced IV treatment is beneficial for those dealing with autoimmune conditions, chronic infections, heavy metal and mold toxicity, as well as brain fog, fatigue, and inflammation. It is often described by patients as a complete reset for the bloodstream.
The EBO2 treatment involves removing the patient's blood from one vein, infusing it with ozone and oxygen through a comprehensive filtration system, and finally passing it through a hemealumination device that uses UVA, UVC, red, green, and blue light to impede viruses and bacteria, energize mitochondria, and activate NAD. On return, the blood, now oxygenated, ozonated, and cleared of impurities, appears bright red, and patients are consistently amazed to see the change from the dark red color at the beginning of the treatment to the bright red color once it has been cleaned.
After an EBO2 treatment, patients can expect to feel reenergized, clearer, and more vibrant. EBO2 is considered one of the most cutting edge treatments available for speeding up recovery and clearing the toxic environmental elements people are exposed to daily, from mold to heavy metals to persistent viral or bacterial burdens.
The science behind ozone and cellular healing
Ozone works by introducing controlled oxidative stress into the body in small, medically calibrated amounts. This might sound counterintuitive, since oxidative stress is often discussed as something to avoid, but at the right dose it triggers a hormetic response, meaning the body responds to a small, manageable stressor by strengthening its own defenses. This includes upregulating antioxidant enzymes, improving how efficiently cells use oxygen, and supporting mitochondrial function, the part of the cell responsible for producing energy. Over a course of treatment, this can translate into the improved energy, mental clarity, and reduced inflammation that many patients report.
This mechanism is part of why ozone therapy has gained traction for chronic, hard to treat conditions where standard approaches have fallen short. Conditions like Lyme disease and certain autoimmune disorders often involve a combination of low grade inflammation, immune dysregulation, and cellular fatigue that ozone based treatments are specifically designed to address from multiple angles at once, rather than targeting a single symptom in isolation.
Research into ozone's clinical applications has expanded considerably over the past two decades, moving the therapy from a fringe alternative approach toward a more established option within integrative and functional medicine practices. While it is not a replacement for conventional treatment of serious underlying conditions, many patients use it as a complementary therapy alongside standard medical care, particularly when standard treatment alone has not fully resolved their symptoms.
What patients commonly report after treatment
While individual results vary, patients who undergo a course of 10 pass ozone therapy or EBO2 commonly describe several recurring themes.
- Improved energy levels that build over the first several sessions rather than appearing after a single visit.
- Mental clarity and reduced brain fog, particularly among patients dealing with chronic fatigue or post infectious symptoms.
- Better sleep quality, which many patients attribute to reduced overall inflammation.
- Fewer flare ups among those managing autoimmune symptoms, though this typically develops over a series of treatments rather than immediately.
Because ozone therapy works cumulatively, patients are encouraged to commit to the recommended treatment schedule rather than judging results after a single session.
How EBO2 differs from 10 pass ozone therapy
Both treatments use ozone to support the body's natural healing processes, but they are built for different goals and work through different mechanisms.
| Feature | 10 pass ozone therapy | EBO2 |
|---|---|---|
| Primary mechanism | Repeated ozonation under hyperbaric pressure | Filtration plus ozonation plus UV light exposure |
| Best suited for | Chronic fatigue, Lyme disease, general anti-aging maintenance | Autoimmune conditions, heavy metal or mold toxicity, chronic infections |
| Typical frequency | Monthly for maintenance, one to two times weekly for active symptoms | Determined individually based on toxic load and condition severity |
| Notable feature | Ten repeated cycles of pressurized ozonation | Visible blood color change from filtration and light exposure |
Dr. Bissoon helps determine which treatment, or combination of treatments, best fits your specific health goals during your initial consultation.
Who is a candidate for ozone based therapies
People considering 10 pass ozone or EBO2 often come in dealing with one or more of the following: persistent fatigue that has not responded to standard treatment, a history of Lyme disease or other tick borne illness, suspected mold or heavy metal exposure, autoimmune symptoms that flare unpredictably, or a general desire to support cellular health and slow visible aging. A consultation with Dr. Bissoon, including a review of your medical history and relevant bloodwork, helps confirm whether ozone therapy is an appropriate fit for your situation.
As with any medical treatment, ozone therapy is not right for everyone. Certain conditions, including specific blood disorders and pregnancy, require caution or may rule out treatment entirely, which is why a proper evaluation always comes before any ozone based therapy begins. Patients on certain medications, particularly blood thinners, are also carefully assessed before treatment to determine the safest approach, and in some cases a modified protocol or a different therapy altogether may be recommended instead.
What to expect during your visit
Both 10 pass ozone therapy and EBO2 are performed in office. A 10 pass session typically takes between 30 minutes and an hour, while EBO2 typically takes between 45 minutes and an hour and a half, depending on the specific protocol used for your session. Blood is drawn through a standard IV line, processed through the treatment equipment, and returned to your body during the same visit. Most patients describe the sensation as similar to a routine blood draw, with no significant discomfort during the ozonation or filtration process itself.
No significant downtime is required afterward. Many patients report feeling immediately more alert or energized following treatment, while others notice benefits building gradually over the following days. Staying well hydrated before and after your session is generally recommended to support your body's response to treatment.
Preparing for your ozone therapy session
A little preparation helps you get the most out of each visit. Staying well hydrated in the days leading up to treatment supports easier blood draws and helps your body process the treatment more comfortably. Eating a light meal beforehand, rather than arriving on an empty stomach, can also help you feel steadier during the session. If you take blood thinning medication or have a bleeding disorder, mention this during your consultation, since it may affect how your treatment is structured.
Most patients find it helpful to plan for a quiet rest period after their first few sessions, even though significant downtime is not typically required, simply to see how their body responds before resuming a full schedule of activity.
Prolozone injections
During prolozone therapy, Dr. Bissoon injects ozone directly to stimulate cellular activity and healing in joints and to relieve muscle pain. This targeted approach is especially useful for localized pain that has not improved with standard treatments, since it delivers ozone precisely to the affected area rather than through the bloodstream more broadly. You have very little downtime after prolozone treatment, and many patients return to normal activity the same day.
Combining ozone therapy with other treatments
Many patients pair ozone based therapies with NAD IV therapy to support cellular energy production alongside the detoxifying and immune boosting effects of ozone. Others combine treatment with bioidentical hormone therapy or regenerative medicine as part of a broader wellness plan. Dr. Bissoon helps map out a combined approach based on your specific symptoms and goals, rather than treating ozone therapy as a standalone fix disconnected from your overall health picture.
Why choose Liondale Medical for ozone therapy in New York City
Liondale Medical was among the first practices in New York City to offer hyperbaric 10 pass ozone therapy, and Dr. Bissoon continues to stay closely involved in advanced protocols like EBO2 as they evolve. Rather than offering a one size fits all treatment, sessions are tailored to your specific health history, symptoms, and goals, with ongoing adjustments made as you progress through treatment. For patients searching for ozone therapy near the Upper West Side or elsewhere in Manhattan, having an experienced, hands on provider matters as much as the technology itself, since protocol selection and dosing decisions benefit substantially from clinical judgment built over years of treating complex, chronic cases.
Contact us today at Liondale Medical by phone or email to learn more about 10 pass ozone therapy, EBO2, or prolozone injections, and to find out which option is the right fit for you.
Frequently Asked Questions
What is the difference between EBO2 and regular ozone therapy?
Regular ozone therapy typically infuses ozone into the blood or tissue directly. EBO2 goes further by combining ozonation with filtration and UV light exposure through a hemealumination device, making it a more comprehensive treatment for autoimmune conditions, toxicity, and chronic infections.
What is 10 pass ozone therapy?
10 pass ozone therapy is a method where blood is repeatedly drawn, mixed with ozone under pressure, and returned to the body across ten cycles, delivering a more concentrated dose of ozone than single pass methods.
How often should I get ozone therapy?
This depends on your goals. Many patients receive 10 pass ozone therapy monthly for general anti-aging maintenance, while those with chronic fatigue or Lyme disease may be treated one to two times per week until symptoms improve. Dr. Bissoon determines your frequency based on your condition and response to treatment.
Is ozone therapy safe?
When administered by a trained provider using medical grade equipment, ozone therapy is generally well tolerated. A thorough evaluation, including medical history and bloodwork, helps confirm you are a good candidate before treatment begins.
How long does an EBO2 treatment take?
EBO2 sessions typically take between 45 minutes and an hour and a half, performed entirely in office with no significant downtime required afterward.
What conditions can ozone therapy help with?
Ozone based therapies are commonly used for chronic fatigue, Lyme disease, autoimmune conditions, mold and heavy metal toxicity, brain fog, and general anti-aging support, among other applications discussed during your consultation.
Can ozone therapy be combined with other treatments?
Yes. Many patients pair ozone based therapy with NAD IV therapy, bioidentical hormone therapy, or regenerative medicine as part of a broader wellness plan. Dr. Bissoon helps determine the right combination based on your specific goals.
What should I do to prepare for an ozone therapy session?
Staying well hydrated and eating a light meal beforehand can help the session go more smoothly. Let Dr. Bissoon know about any blood thinning medications or bleeding disorders during your consultation, since these may affect how treatment is structured.

