What is Therapeutic Plasma Exchange?

Therapeutic Plasma Exchange is a clinically sophisticated procedure that removes and replaces the plasma portion of your blood with a purified protein solution. By clearing

inflammatory proteins, senescent factors, and other harmful substances that accumulate over time, TPE creates an optimized internal environment where your body can perform, repair, and regenerate at peak capacity.

Your blood carries far more than oxygen and nutrients—it transmits critical signals related to inflammation, cellular repair, immune function, and biological aging. When these signals fall out of balance, the effects manifest as diminished energy, cognitive

decline, persistent inflammation, and accelerated aging. TPE helps restore this balance.

The Science of Biological Age Reversal

Recent peer-reviewed research published in Aging Cell (2025) demonstrates that

participants receiving TPE with IVIG showed an average biological age reduction of 2.6 years after just six sessions. This groundbreaking study utilized multi-omics

analysis to identify specific biomarkers contributing to age rejuvenation.

TPE has been clinically recognized by the American Society for Apheresis and leading medical organizations as a safe, effective treatment for inflammatory and

immune-related conditions. Our medical team brings this established therapeutic approach to the optimization of healthspan and vitality.

Benefits for High-Performing Individuals

Our patients choose TPE to:

• Reduce chronic inflammation linked to fatigue, persistent discomfort, and cognitive fog
• Support longevity by maintaining optimal circulation and immune balance
• Enhance recovery and performance for executives, athletes, and high achievers
• Boost cognitive clarity, sustained energy, and physical vitality
• Complement existing therapies for autoimmune, metabolic, and neurodegenerative conditions

Many patients describe experiencing renewed mental clarity, improved stamina, and an overall sense of vitality and resilience following their treatment series.

The Liondale Experience

Your Treatment Session

Each TPE session takes approximately two to three hours in our private, comfortable clinical setting. You will be attended throughout by a highly skilled apheresis nurse who specializes in this advanced procedure. During treatment, your blood gently cycles through the apheresis device where plasma is separated and replaced with

pharmaceutical-grade albumin. Your red blood cells, white blood cells, and platelets are safely returned to your body.

Patients typically read, work, or rest during their session. Vital signs and comfort are continuously monitored to ensure a seamless experience.

IVIG Enhancement

As part of our clinical protocol, Intravenous Immunoglobulin (IVIG) may be incorporated alongside TPE to replenish healthy antibodies and further support

immune balance. This enhancement is commonly offered to optimize recovery and resilience, unless contraindicated.

Who Should Consider TPE

Therapeutic Plasma Exchange is ideal for:

Proactive Health Optimizers

You take a sophisticated approach to aging well, prioritizing vitality, longevity, and prevention. You invest in cutting-edge interventions that deliver measurable results.

Those Managing Chronic Inflammation

You experience ongoing symptoms—fatigue, brain fog, persistent discomfort—that affect your performance and quality of life. You're seeking advanced solutions beyond conventional approaches.

High Performers Maintaining Peak Function

You value sustained cognitive sharpness, physical resilience, and the ability to perform at the highest levels as you age. You refuse to accept decline as inevitable.

Why Choose Liondale Medical

As one of the few practices in New York offering on-site Therapeutic Plasma Exchange, Liondale Medical brings decades of expertise in integrative and regenerative medicine to this sophisticated intervention. Our concierge model ensures personalized care,

comprehensive monitoring, and seamless coordination with your existing wellness protocols.

We understand that our patients demand excellence, discretion, and results. TPE represents the convergence of rigorous medical science and the art of longevity medicine—delivered with the attention to detail and clinical precision that defines Liondale Medical.

Exceptional Patient Satisfaction

According to Circulate's post-procedure patient surveys, 90% of patients report high satisfaction with their TPE experience. Patients consistently describe feeling clearer, lighter, and more energized in the hours and days following treatment.

Begin Your Journey

Availability for Therapeutic Plasma Exchange will be limited as we launch this service. We are currently finalizing logistics and will begin scheduling soon.

To express interest or learn more about whether TPE is right for you, please contact our office directly. Our team will be pleased to discuss your wellness goals and determine if this advanced intervention aligns with your personalized care plan.

Liondale Medical

Upper West Side, Manhattan

Concierge Wellness & Integrative Medicine